UZCHS-CTRC would like to congratulate two of our research scientists for leading and publishing two articles in high-impact journals.
Published in AIDS and Behavior, Petina Musara led the authorship of a paper on how presenting drug detection levels in blood changed self-reports of study product adherence in the MTN 003 (VOICE) study. MTN 003-D was a qualitative study designed to better understand non-adherence during VOICE, and was conducted in 2 stages: before (stage 1) and after (stage 2) drug detection results were provided to participants. The study found that presenting objective measures of study product use may facilitate more accurate use reporting and should be evaluated in future prevention trials. (https://www.ncbi.nlm.nih.gov/pubmed/28110473). Petina is CRS Coordinator at Zengeza Clinical Research Site in Chitungwiza, Zimbabwe.
Dr. Samaneka led the authorship of a paper that established updated hematology and chemistry laboratory reference ranges for local Zimbabwean adults. Published in PLoS One, the authors discuss that laboratory reference ranges used for clinical care and clinical trials at laboratories in Zimbabwe are derived from textbooks and research studies conducted more than 10 years ago. Periodic verification of these ranges is essential to track changes over time. The purpose of this study was to establish hematology and chemistry laboratory reference ranges using more rigorous methods. Data from this study provides new country-specific reference ranges which should be immediately adopted for routine clinical care and accurate monitoring of adverse events in research studies. (https://www.ncbi.nlm.nih.gov/pubmed/27812172). Dr. Samaneka is Senior Medical Officer at Parirenyatwa Clinical Research Site in Harare, Zimbabwe.