Sponsors: US National Institutes of Health (NIH)
Protocol Summary: Combined oral contraceptives (COC) and depot-medroxyprogesterone acetate (DMPA) are among the most widely used family planning methods; their effect on HIV acquisition is unknown. This multicenter, prospective cohort study enrolled over 6,000 HIV-uninfected women, aged 18-35 years, from family planning clinics in Uganda, Zimbabwe and Thailand. The study evaluated the effects of COC and DMPA on HIV acquisition and any modifying effects of other sexually transmitted infections.
Years: 2000 – 2005
Investigator: Tsungai Chipato, MBChB, FRCOG, MCE
Location: Spilhaus and Seke South CRSs
Morrison CS, Richardson BA, Mmiro F, Chipato T, Celentano DD, et al. (2007) Hormonal contraception and the risk of HIV acquisition. AIDS; 21(1): 85-95.